dimanche 12 mai 2019

L'INSTA et la NEWS du jour



Ou quand le photographe Mark Sullivan Bradley est fier de faire la couverture du Sunday Telegraph avec une superbe photo d'ONJ ! Surtout lorsque le sujet Ă  son importance !

Une prise de sang pour le cancer du sein est en passe de remplacer la mammographie. C’est un cadeau offert aux femmes par Olivia Newton-John Ă  l’occasion de la fĂŞte des mères.
Développé par des chercheurs de l'Institut de recherche sur le cancer Olivia Newton-John, le test servira dans un premier temps à vérifier si le cancer a récidivé chez les 18 000 Australiennes diagnostiquées et traitées pour le cancer du sein chaque année.
Le test doit être testé cliniquement d'ici trois ans ....




Blood test for cancer in sight



OLIVIA’S GIFT
Breast cancer blood test that scientists believe will one day replace the mammogram

The Sunday Telegraph (Sydney)
12 May 2019
SUE DUNLEVY



A REVOLUTIONARY blood test that could one day replace mammograms to detect breast cancer has been developed by the
research unit set up by Australian superstar Olivia Newton-John.
The test, that identifies DNA specific to breast cancer, will be trialled in the next three years in women who have already had treatment for the disease.
But in a long- desired Mother’s Day gift for women, the test’s creator
Associate Professor
Alexander Dobrovic hopes it will eventually be developed to replace mammograms for all breast-cancer screening.
IT is the holy grail of breast cancer treatment — a blood test to replace the mammogram.
In a Mother’s Day gift, researchers at the Olivia Newton-John Cancer Research Institute have developed the test that identifies DNA unique to breast cancer.
It is scheduled to be in clinical trials within three years and will initially be used to check whether cancer has returned in the 18,000 Australian women diagnosed and treated for the disease each year.
But Associate Professor Alexander Dobrovic, who is behind the test, hopes one day it can be refined to replace mammograms for all breast cancer screening.
“Early detection is definitely one of the holy grails,” he said. “There is the potential to modify this to be used in early detection.”
The new test works differently from scans and invasive tissue biopsies by searching blood samples for 10 cancer markers that cover more than 99 per cent of all breast cancers.
The amount of tumour DNA a patient has is directly related to the amount of cancer.
“We isolate the DNA from the blood then do a molecular technique to identify if there is DNA coming from cancer,” Prof Dobrovic said.
“If you can’t detect the DNA there is no disease or it is very low.”
Those found to be carrying the cancer DNA would then need scans to find out where it has spread and determine the most effective treatment.
The test could be used every three months in women who already have breast cancer to check if the disease returns after treatment.
However, to be effective as an early intervention screening test, it would need to be refined to identify all women who have breast cancer, not just those already treated.
While early detection is not the focus of Prof Dobrovic’s research, his work is important to fellow scientists studying cancer.
The aim is to get the price of the test below the cost of a scan.
Prof Dobrovic works at the cancer institute set up by Australian singer and movie star Olivia Newton-John (pictured right), best known for her role in the movie Grease. In September, Newton-John, 70, confirmed she was fighting cancer for the third time.




The four-time Grammy winner was first diagnosed with breast cancer in 1992, undergoing a partial mastectomy and reconstruction. She was diagnosed the weekend her father died from cancer.
She battled cancer again in 2013 but kept the illness private.
One in eight Australian women will be diagnosed with breast cancer in their lifetime.
Prof Dobrovic’s breast cancer research project has won a $385,000 grant from the National Breast Cancer Foundation, which has awarded more than $9.2 million in its bid to reduce breast cancer deaths to zero.
“We are thrilled to be awarding $9.2 million to such groundbreaking research. This is a promising step as we strive towards zero deaths from breast cancer,” foundation CEO Professor Sarah Hosking said.
The most common cancer in women is usually detected using mammogram screening from age 50.
Prof Dobrovic, who has also been involved in developing a blood test to detect the return of melanoma, said his work would be useful to other teams of scientists working on cancer screening blood tests.
The research team is working with oncologist Dr Belinda Yeo and Dr James McCracken, who are collecting bloods from patients who have metastatic breast cancer so they can optimise the test.
A Silicon Valley company, Grail Inc, is also working on a blood test for tumour DNA that could be used to screen for a range of cancers before symptoms appear using artificial intelligence and high-intensity sequencing, but so far it has detected only one in four cases of breast cancer.
Johns Hopkins University researchers last year revealed they had developed a blood test that could detect eight cancers.



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Un grand merci Ă  Kay pour ses collaborations !

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